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2025/04/09
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Dr Serene Goh

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Designations:

  • Consultant, Division of General Surgery (Breast Surgery), Department of Surgery, National University Hospital
  • Consultant, Division of General Surgery, Alexandra Hospital

Qualifications:

MBBS (Singapore), MRCS (Edinburgh), M.Med (Surgery), FRCS (Edinburgh), USMLE (ECFMG)

Specialties/Sub-specialties:

General Surgery

Clinical Disciplines/Programmes:

Breast Surgery, Surgery, Surgical Oncology

Special Interests:

Minimally invasive and endoscopic mastectomy (nipple-sparing and skin-sparing) with or without breast reconstruction, Oncoplastic surgery for breast conservation, Chest wall perforator flap-based reconstruction for wider defects, Therapeutic mammoplasty and contralateral symmetrising mammoplasty, Fat grafting after cancer resection, Prophylactic and risk-reducing surgery, Wire and non-wire localisation for breast and axillary surgery, Sentinel lymph node biopsy and targeted axillary dissection, Axillary lymph node dissection, Ultrasound guided core biopsy, vacuum-assisted biopsy/excision and cryotherapy




Biosketch

Dr Serene Goh is a breast surgical oncologist at the National University Hospital (NUH), Singapore, specialising in oncoplastic and minimally invasive breast surgery. Central to her surgical philosophy is minimising the physical and emotional impact of breast cancer treatment. She achieves this through breast-conserving oncoplastic techniques wherever possible, and where mastectomy is necessary, through minimally invasive nipple-sparing approaches with reconstruction, in close collaboration with the plastic surgery team.

Her practice spans the full continuum of breast surgical oncology from oncoplastic reconstruction and complex multidisciplinary cases, to tailored care for older patients, and risk-reducing surgery for young and high-risk individuals. Her specialty interests encompass oncoplastic procedures including chest wall perforator flap based reconstruction, therapeutic and symmetrizing mammoplasties, minimally invasive and endoscopic mastectomy, vacuum-assisted biopsy/ excision and cryotherapy, as well as wire-based or non-wire localisation techniques.

Patient-centred care is at the heart of her practice. She works collaboratively with patients to reach decisions that are oncologically sound and aligned with their individual values and goals, ensuring they feel informed, heard, and supported throughout their journey. Her dedication to compassionate care has been recognised through the Incredible Care Service Champion Award in 2025 and 2026, and the Singapore Health Service Award in 2026.

Dr Goh obtained her Bachelor of Medicine and Bachelor of Surgery (MBBS) from the National University of Singapore (NUS) Yong Loo Lin School of Medicine in 2015. She subsequently obtained her Membership of the Royal College of Surgeons (MRCS) from Edinburgh, followed by her Master of Medicine in Surgery (MMed), her Fellowship of the Royal College of Surgeons (FRCS) from Edinburgh, and her Fellowship of the Academy of Medicine, Singapore (FAMS). She is an Adjunct Senior Lecturer at NUS Yong Loo Lin School of Medicine. She completed her PhD at the Saw Swee Hock School of Public Health, NUS, with a focus on AI in breast oncology. She has undertaken fellowship training in oncoplastic surgery, targeted axillary dissection and multidisciplinary oncology at the Royal Marsden Cancer Centre, London, fat grafting after breast cancer surgery at the Edinburgh Breast Unit, and robotic breast surgery programmes in South Korea.

She has a keen interest in emerging localisation technologies, including novel non-wire localisation devices for breast lesions and lymph nodes, and is actively involved in evaluating and adopting innovations that enhance surgical precision, reduce procedural burden, and improve the overall experience for patients undergoing breast surgery. As a clinician-scientist, she leads and co-leads multiple research grants spanning AI-augmented breast cancer screening, surgical innovation, and cancer survivorship. She mentors students and trainees across NUS and the Nanyang Technological University, and collaborates widely across Asia Pacific with a shared goal of improving breast cancer outcomes for women in the region.

Awards

  • Healthcare Excellence and Patient Care: Singapore Health Service Award (2026)
  • Compassionate and Patient-Centred Practice: NUHS Incredible Care Service Champion Awards (2025, 2026)
  • Endoscopic Mastectomy: Top Video Presentation, Singapore Breast Oncoplastic Surgery Symposium (2025)
  • Oncoplastic Surgery:  Vertical Mammoplasty with Conal Rotation and Anterior Intercostal Perforator Flap Video Presentation Finalist, Singapore Breast  (2023)
  • BreastGuard: Radiolucent Specimen Holder for Safer Hookwire Transport and Margin Standardisation — Letter of Commendation, Best Team Finalist, Singapore Health Quality Service Awards (2026)
  • Mastectomy versus Breast-Conserving Surgery in Paget's Disease: A Systematic Review and Meta-Analysis — Best Poster Presentation Award, Global Breast Cancer Conference, Korea (2023)
  • AI-Augmented Mammography Screening: Maximising Detection of Normal Mammograms — Young Investigator Award, Global Breast Cancer Conference, Korea (2023)
  • AI versus Tomosynthesis in Detecting Interval Breast Cancers: A Crossover Trial — Best Oral Presentation, Global Breast Cancer Conference, Korea (2025)
  • Medical Education and Student Mentorship: Dean's Award for Teaching Excellence, NUS Yong Loo Lin School of Medicine (2022, 2023, 2024, 2025)
  • MEGIC Medical Education Grant Innovation Challenge: Special Mention Award (2023) For The Knife Life Podcast, a student-facing initiative on Spotify aimed at inspiring undergraduates to pursue a career in surgery

Journals & Publications

  1. Augmenting large language models with NCCN guidelines for improved and standardized adjuvant therapy recommendations in postoperative breast cancer cases Journal of Clinical Oncology — Clinical Cancer Informatics (2025) Serene Si Ning Goh, Ragunathan Mariappan, Grace Soo Woon Tan, Jiali Yao, Fook Ming Hew, Yenshing Yeo, Samuel Guan Wei Ow, Wee Yao Koh, Nesaretnam Barr Kumarakulasingh, Teng Hwee Tan, Bee Choo Tai, Mikael Hartman, Kee Yuan Ngiam
  2. Systematic Review of Challenges in Implementing Artificial Intelligence in Breast Cancer Screening Programs: Towards a Framework for Safe Adoption Journal of Medical Internet Research (2024) Serene Si Ning Goh, Rachel Sze Jen Goh, Bryan Chong, Qin Xiang Ng, Gerald Choon Huat Koh, Kee Yuan Ngiam, Mikael Hartman
  3. Impact of AI on Breast Cancer Detection Rates in Mammography by Radiologists of Varying Experience Levels in Singapore: Preliminary Comparative Study JMIR Formative Research (2025) Serene Si Ning Goh, H Du, LY Tan, EZY Seah, WK Lau, AHZ Ng, SWD Lim, HY Ong et al.
  4. From promise to practice: Harnessing artificial intelligence for breast cancer screening Intelligent Oncology (2025, invited article) Serene Si Ning Goh, Mikael Hartman
  5. Comparing outcomes following breast conserving surgery with radiotherapy versus total mastectomy in patients with Paget's disease of the breast: A systematic review and meta-analysis British Journal of Surgery (2023) Serene Si Ning Goh, Nicholas Li-Xun Syn, Cheryl Jia En Lim, Rui En Lee, Miny Samuel, Celene Wei Qi Ng
  6. Oncological outcomes following extreme oncoplastic breast conserving surgery for locally advanced breast cancer: A systematic review and meta-analysis The Breast (2024) Megan Chua Wern Ee, Ashley Lee Shi Hui, Wong Hung Chew, Emmeline Elaine Cua-Delos Santos, Sean Li Siwei, Sng Ming Xian, Qin Xiang Ng, Serene Si Ning Goh
  7. Harnessing Artificial Intelligence to Enhance Global Breast Cancer Care: A Scoping Review of Applications, Outcomes, and Challenges Cancers (2025) Jolene Li Ling Chia, George Shiyao He, Kee Yuen Ngiam, Mikael Hartman, Qin Xiang Ng, Serene Si Ning Goh
  8. Utility of photoacoustic patterns in intra-operative margin assessment of breast cancer post neoadjuvant chemotherapy Photoacoustics (2025) Yonggeng Goh, Serene Si Ning Goh, Wei Qi Leong, Eric Fang, Swee Tian Quek, Malini Olivo
  9. Cryotherapy as a Surgical De-Escalation Strategy in Breast Cancer: Techniques, Complications, and Oncological Outcomes Biomedicines (2025) KL Lee, AA Sule, HX Lai, QX Ng, Serene Si Ning Goh
  10. Supraclavicular Lymph Node Dissection in Breast Cancer with Synchronous Supraclavicular Metastases: A Systematic Review and Network Meta-Analysis Cancers (2025) George Shiyao He, Jolene Li Ling Chia, Emmeline Elaine Cua-De Los Santos, Wong Hung Chew, Wee Yao Koh, Qin Xiang Ng, Samuel Ow, Serene Si Ning Goh

Professional Memberships

  • The Royal College of Surgeons of Edinburgh
  • Fellow - Academy of Medicine, Singapore (FAMS)
  • Member - National University Hospital, Blood Usage Committee

2026/03/19
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National University Health System
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  • National University Polyclinics
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  • National University Cancer Institute, Singapore
  • National University Heart Centre, Singapore
  • National University Centre for Oral Health, Singapore
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  • NUS Yong Loo Lin School of Medicine
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